Sep 2004-Jun 2008 Bachelor degree of Science in Biotechnology, Tianshui Normal University, China
Sep 2008-Jun 2013 PhD in Biochemistry and Molecular Biology under supervision of Prof. Dr. Qiang Chen, Lanzhou University, China
Sep 2011-Apr 2013 Joint PhD student in Chemical Biology under supervision of Dr. Gemma Triola, Max-Planck-Institut für molekulare Physiologie, Germany
Sep 2013-Dec 2017 Postdoctoral Research Fellow, Max-Planck-Institut für molekulare Physiologie, Germany
Jan 2018-Present Principal Investigator, Assistant Professor with Tenure Track, School of Life Sciences, Chongqing University, China
Research interests
1. Elucidating the mechanism of autophagy using chemical biological tools
2. Chemical biology of proteins with posttranslational modification
Any students are welcome to join our group to pursue master or PhD research. We are seeking a highly motivated postdoctoral researcher who is interested in autophagy and has a background of cell biology and biochemistry.
Academic position
No
Major achievement
Current Grants
1. Major Research Plan of the National Natural Science Foundation of China (No.91854101), 01/01/2019-12/31/2021, PI:Aimin Yang
2. National Natural Science Foundation of China (No.31801166), 01/01/2019-12/31/2021, PI:Aimin Yang
3. Chongqing Science and Technology Commission (No.cstc2018jscx-msybX0333), 07/01/2018-06/30/2020, PI:Aimin Yang
4. Fundamental Research Funds for the Central Universities (No.2018CDQYSM0037), 01/01/2018-12/31/2019, PI:Aimin Yang
5. Chongqing University “100 Youth Talents plan” Start-up grant (No.0304001104427), PI:Aimin Yang
Publications
● Ligang Mei, Xiaofeng Qiu, Chen Jiang, Aimin Yang*. Host delipidation mediated by bacterial effectors. Trends in Microbiology 2021, 29(3):238-250
● Aimin Yang#, Supansa Pantoom#, Yao-Wen Wu*. Distinct mechanisms for processing autophagy protein LC3-PE by RavZ and ATG4B. ChemBioChem 2020, 21(23):3377-3382.
● Xue Huang, Chen Jiang, Lihua Yu, Aimin Yang*. Current and emerging approaches for studying inter-organelle membrane contact sites. Frontiers in Cell and Developmental Biology 2020, 8, 195
● Yu Luo, Chen Jiang, Lihua Yu, Aimin Yang*. Chemical biology of autophagy-related proteins with posttranslational modifications: from chemical synthesis to biological applications. Frontiers in Chemistry 2020, 8, 233
● Aimin Yang#, Supansa Pantoom#, Yao-Wen Wu. Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins. eLife 2017, 6:e23905. [# equal contribution]
This article was featured in EurekAlert (online press service created by the American Association for the Advancement of Science (AAAS)) (https://www.eurekalert.org/pub_releases/2017-04/e-lbe041017.php), ScienceDaily (https://www.sciencedaily.com/releases/2017/04/170411085754.htm) and Ebiotrade (http://www.ebiotrade.com/newsf/2017-4/2017410142728580.htm).
● Supansa Pantoom#, Aimin Yang#,Yao-Wen Wu. Lift and cut: anti-host autophagy mechanism of Legionella pneumophila. Autophagy 2017, 13(8):1467-1469. [# equal contribution]
● Aimin Yang, Inken Hacheney, Yao-Wen Wu. Semisynthesis of autophagy protein LC3 conjugates. Bioorganic & Medicinal Chemistry 2017, 25(18):4971-4976.
● Aimin Yang#, Lei Zhao#, Yao-Wen Wu. Chemical synthesis and biological function of lipidated proteins. Topics in Current Chemistry 2015, 362:137-182. [# equal contribution]
● Aimin Yang, Yanping Li, Supansa Pantoom, Gemma Triola, Yao-Wen Wu. Semisynthetic lipidated LC3 protein mediates membrane fusion. ChemBioChem 2013, 14(11):1296-1300.
This article was selected as Front Cover Story in ChemBioChem.
● Shaobin Yang, Aimin Yang, Tingji Shao, Shufang Su, Qiang Chen. Synergistic analgesic effects between neuronostatin and morphine at the supraspinal level. Peptides 2013, 44(6):105-110.
● Jiarun Mo, Aimin Yang, Zilong Chen, Tingji Shao, Yang Zhang, Qiang Chen. Neuronostatin ameliorates sodium taurocholate-induced acute pancreatitis in rats. Digestive Diseases and Sciences 2013, 58(10):2903-2907.
● Aimin Yang#, Wanwen Ge#, Songsong Lu, Shaobin Yang, Shufang Su, Zeyun Mi, Qiang Chen. Central administration of neuronostatin induces antinociception in mice. Peptides 2011, 32(9):1893-1901. [# equal contribution]
● Shufang Su#, Aimin Yang#, Shaobin Yang, Ningbo Wang, Songsong Lu, Huihui Wang, Qiang Chen. Intracerebroventricular administration of neuronostatin delays gastric emptying and gastrointestinal transit in mice. Peptides 2012, 35(1):31-35. [# equal contribution]
● Shaobin Yang#, Aimin Yang#, Shufang Su, Huihui Wang, Ningbo Wang, Qiang Chen. Neuronostatin induces hyperalgesia in formalin test in mice. Neuroscience Letters 2012, 506(1):126-130. [# equal contribution]
● Aimin Yang, Yue-ke Ji, Shufang Su, Shaobin Yang, Songsong Lu, Zeyun Mi, Qingzhen Yang, Qiang Chen. Intracerebroventricular administration of neuronostatin induces depression-like effect in forced swim test of mice. Peptides 2011, 32(9):1948-1952. [# equal contribution]
Awards
No
Postgraduate training
3 PhD candidate, 6 master students
Contact information
E-mail：aimin.yang@cqu.edu.cn
