Personal profile
2000 - 2004 BS, Sichuan University
2004 - 2010 PhD, Shanghai Institutes for Biological Sciences
2011 - 2014 Postdoc, University of Southern California, US
2014 - now PI, Professor, Chongqing University
Research interests
Aging is a big risk factor for many chronic diseases, which are named "Aging-related diseases". Mechanisms that retard aging process generally prevent the onset of aging-related diseases. Our lab is interested in deciphering the metabolic mechanisms of aging and longevity, seeking to identify novel metabolites that regulating animal lifespan and uncover the underlying molecular mechanisms.
Major achievement
Selected publications（* correspondence）
1. Wang F#, Dai Y#,…,Tang H*, Pang S*. Saturated very long chain fatty acid configures glycosphingolipid for lysosome homeostasis in long-lived C. elegans. Nature Communications. 2021, 12:5073 (Nature子刊)
2. He B, Xu J, Pang S*, Tang H*. Phosphatidylcholine mediates the crosstalk between LET-607 and DAF-16 stress response pathways. PLoS Genet. 2021, 17(5): e1009573. (自然指数期刊)
3. Deng J#, Bai X#, Tang H*, Pang S*. DNA damage promotes ER stress resistance through elevation of unsaturated phosphatidylcholine in C. elegans. J Biol Chem. 2021, 296:100095.（自然指数期刊）
4. Zhou L, He B, Deng J, Pang S*, Tang H*. Histone acetylation promotes long-lasting defense responses and longevity following early life heat stress. PLoS Genet. 2019, 15(4): e1008122. (自然指数期刊)
5. Tang H*, Pang S*. Proline catabolism modulates innate immunity in C. elegans. Cell Reports. 2016, 17(11): 2837-2844. (Cell子刊)
6. Pang S#, Lynn D#, Lo J, Curran SP. SKN-1 and Nrf2 couples proline catabolism with lipid metabolism during nutrient deprivation. Nature Communications. 2014, 5:5048. (Nature子刊)
7. Pang S, Curran SP. Adaptive capacity to bacterial diet modulates aging in C. elegans. Cell Metabolism. 2014, 19(2): 221-231. (Cell子刊). (Previewed as a leading edge finding in Cell Metabolism)
